Although they are crucially important, a person's total calorie intake is only one of the many factors that determine if their weight will increase or decrease.
they are crucially important, a person's total calorie intake is only one of the many factors that determine if their weight will increase or decrease
it is crucially important, a person's total calorie intake is only one of the many factors that determine whether his or her weight will increase or decrease
it is a crucially important factor, a person's total calorie intake is the only one of many that determines whether his or her weight will increase or decrease
crucially important, a person's total calorie intake is only one of the many factors that determines the increase or decrease in their weight
it is crucially important, a person's total calorie intake is the only one of many factors that determines the increase or decrease in his or her weight
I eliminated the 4th choice above on the basis of the requirement that although should be followed by a clause.
Hope its correct.